MCQ’S ON APOPTOSIS
1. This is an extracellular messenger of apoptosis
(a) tumor necrosis factor
(b) serine
(c) translation inhibitor
(d) ribozyme
Answer: (a)
2. This is concerned with the intrinsic pathway of apoptosis
(a) cytochrome d
(b) cytochrome c
(c) cytochrome b
(d) cytochrome a
Answer: (b)
3. Apoptotic bodies can be recognized with the presence of these on the surface
(a) phosphatidyl tyrosine
(b) phosphatidylinositol
(c) phosphatidylcholine
(d) phosphatidylserine
Answer: (d)
4. Apoptotic cells detach due to the inactivation of this
(a) PKC
(b) PKB
(c) RAF1
(d) FAK
Answer: (d)
5. Shrinking of the nucleus is caused when this inactivates
(a) gelsolin
(b) tubulin
(c) actin
(d) lamin
Answer: (d)
6. This cell organelle participates actively in animal apoptosis
(a) nucleus
(b) vacuoles
(c) mitochondria
(d) chloroplast
Answer: (c)
7. This can stimulate cytochrome release from mitochondria
(a) Akt
(b) Bid
(c) Bad
(d) Smac
Answer: (b)
8. This cannot be killed by apoptosis
(a) immune cells
(b) cells with DNA damage
(c) cancer cells
(d) a cell infected with viruses
Answer: (c)
9. This is an anti-apoptotic protein
(a) Bim
(b) Bcl-Xs
(c) Bfl 1
(d) NOXA
Answer: (c)
10. This is an active cell death process
(a) necrosis
(b) lysis
(c) apoptosis
(d) senescence
Answer: (c)
